Haematologica Reports 2005; 1(issue 9): 54-55
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Bleeding and thrombosis in childhood
cancer
Nowak-Göttl U
Department of Pediatric Hematology/Oncology, University of
Münster, Germany
Defects of hemostasis in patients with cancer have been first
described by Trousseau in 1865,1 and Morrison studied
altered coagulation in patients with malignancy as early as
1932.2 The first described abnormality of hemostasis in
malignancy was that of hypercoagulability and thrombosis and the
first large survey of blood changes in cancer patients showed
accelerated bleeding times in over 60% of patients studied. This
presentation discusses thrombotic and hemorrhagic disorders that
occur in children with solid tumors and hematological malignancies.
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